Statistically significant differences from control group (P < 0.05, Mann-Whitney test).
Article: Calcium imaging in single neurons from brain slices using bioluminescent reporters.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Drobac E; Tricoire L; Chaffotte AF; Guiot E; Lambolez B J. Neurosci. Res., 2010
Control (n = 8) | GA (n = 12) | GO (n = 18) | GAN26D (n = 9) | GAEGTA-free (n = 11) | |
---|---|---|---|---|---|
| |||||
Resting membrane potential (mV) | −60.6 ± 2.2 | −65.4 ± 3.5* | −62.5 ± 2.5 | −61.4 ± 5.2 | −62.5 ± 2.4 |
Input resistance (MΩ) | 176.3 ± 79.4 | 269.1 ± 130.2 | 217.1 ± 46.1* | 187.8 ± 37.3 | 189.1 ± 28.8 |
Spike threshold (mV) | −40.1 ± 3.3 | −39.6 ± 2.4 | −38.8 ± 2.3 | −38.7 ± 2.9 | −38.6 ± 1.9 |
First spike amplitude (mV) | 108.9 ± 11.6 | 106.3 ± 4.4 | 107.7 ± 6.5 | 106.4 ± 6.7 | 106.7 ± 4.5 |
First spike duration (msec) | 1.2 ± 0.2 | 1.1 ± 0.2 | 1.2 ± 0.2 | 1.2 ± 0.1 | 1.1 ± 0.2 |
First AHP (mV) | −10.8 ± 4.9 | −14.6 ± 4.2 | −12.3 ± 4.5 | −10.3 ± 2.8 | −10.9 ± 2.4 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Neocortex pyramidal cell layer 5-6 | Neocortex Layer V Pyramidal Cell | spike threshold (mV) | -40.1 ± 3.3 (8) | -40.1 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Neocortex Layer V Pyramidal Cell | spike amplitude (mV) | 108.9 ± 11.6 (8) | 108.9 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Neocortex Layer V Pyramidal Cell | spike half-width (msec) | 1.2 ± 0.2 (8) | 1.2 (ms) | Data Table |
Neocortex pyramidal cell layer 5-6 | Neocortex Layer V Pyramidal Cell | resting membrane potential (mV) | -60.6 ± 2.2 (8) | -60.6 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Neocortex Layer V Pyramidal Cell | AHP amplitude (mV) | -10.8 ± 4.9 (8) | 10.8 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Neocortex Layer V Pyramidal Cell | input resistance (MΩ) | 176.3 ± 79.4 (8) | 176.3 (MΩ) | Data Table |